Hyperpigmented macules surrounded by hypopigmented rim in a case of lepromatous leprosy
pdf

Keywords

Leprosy
Multidrug therapy
Woronoff’s ring
Hypopigmented halo
Mycobacterium leprae

How to Cite

1.
Mushtaq S. Hyperpigmented macules surrounded by hypopigmented rim in a case of lepromatous leprosy: an atypical presentation. Hansen. Int. [Internet]. 2024 Nov. 22 [cited 2024 Dec. 4];49:1-7. Available from: https://periodicos.saude.sp.gov.br/hansenologia/article/view/40192

Abstract

Introduction: leprosy is a chronic infectious mycobacterial disease caused by M. leprae. It primarily involves the skin and nerves, presenting with skin lesions and nerve enlargement. The skin lesions vary from hypopigmented, anesthetic macules/plaques to erythematous papules, plaques, and nodules, depending upon the type of leprosy.
Hyperpigmented lesions in leprosy are rarely reported. Although hypopigmented lesions are commonly seen, perilesional hypopigmentation is a rare occurrence in leprosy. Perilesional hypopigmentation is seen as Woronoff’s ring around resolving lesions of psoriasis. A similar phenomenon called the halo phenomenon is associated with various skin tumors. Case Presentation: we describe a rare presentation of a leprosy case presenting with hyperpigmented lesions surrounded by a perilesional hypopigmented rim.

https://doi.org/10.47878/hi.2024.v49.40192
pdf

References

1. Jopling WH, McDougall AC. Handbook of Leprosy. 5th ed. New Delhi: CBS Publishers; 1996. p. 1-7.

2. Kumar B, Dogra S. Case definition and clinical types of leprosy. In: Kumar B, Kar HK. IAL Textbook of leprosy. 2nd ed. New Delhi: Jaypee; 2017. p. 238-50.

3. Abideen F, Balakrishnan S, Sindhu CB, George S, Sanker A. A unique case of borderline lepromatous leprosy presenting with both hypopigmented and hyperpigmented macules. Lepr Rev. 2021;92(4):412-20. doi: https://doi.org/10.47276/lr.92.4.412.

4. Arakkal GK, Vani S, Kasetty HK, Varala S. Leprosy: an unusual presentation. Int J Med Public Health. 2015[cited 2023 Jun 15];5(1):118-20. Available from: https://www.ijmedph.org/Uploads/Volume5Issue1/IntJMedPubHealth-5-1-118.pdf.

5. Singh SN, Gardin HK, Bhattamishra AB. Hyperpigmented lesions in Hansen’s disease. Indian J Dermatol. 1999; 44(4):215-6.

6. Chattopadhyay SP, Gupta CM. Primary hyperpigmented cutaneous lesions in tuberculoid leprosy. Indian J Lepr. 1988;60(1):63-5.

7. Mehta VR. The primarily pigmented tuberculoid leprosy. Int J Lepr. 1984;52(Suppl):687-8.

8. Okhandiar RP, Sinha E, Sinha RK. Leprous lesion with hyperpigmented border. Indian J Lepr. 1985;57:640-3.

9. Grover S, Singh G, Dash K. Primary hyperpigmented palmar lesion: a rare presentation of borderline tuberculoid leprosy. Indian J Lepr. 1997;69:191-3.

10. Awali R, Chandrasekar PH. Hyperpigmented macule on the palm and diminished sensation. J Am Med Assoc. 2018;320(19):2029-30. doi: https://doi.org/10.1001/jama.2018.14701.

11. Shereef PH, Thomas M. Hypopigmented macules in leprosy: a histopathological and histochemical study of melanocytes. Indian J Lepr. 1992;64(2):189-91. Erratum in: Indian J Lepr. 1992;64(3):301.

12. Van Brakel WH. Peripheral neuropathy in leprosy and its consequences. Lepr Rev. 2000;71(Suppl.1):146-53. doi: https://doi.org/10.5935/0305-7518.20000086.

13. Kumar P, Sawant SS, Das A. A curious case of lepromatous leprosy developing complete loss of pigmentation, followed by reappearance of pigmentation with multidrug therapy (MDT) alone: a support of neural theory of vitiligo pathogenesis? Indian J Lepr. 2018[cited 2023 Jul 25];90:155-9. Available from: https://www.ijl.org.in/publishedarticles/14092021150718/8_P_Kumar_et_al_(CR)_(155-159).pdf.

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

Copyright (c) 2024 Sabha Mushtaq

Downloads

Download data is not yet available.