Identificação de um paciente com hanseníase multibacilar por meio do teste sorológico (LID) em ações de busca ativa: um relato de caso

Heloine Martins Leite; Marcos Daniel Silva Pinheiro; Daisy Cristina Monteiro dos Santos; Karolina Dias Campos; Lorena Bruna Pereira de Oliveira; Lucia Alves de Oliveira Fraga

doi:10.47878/hi.2023.v48.39317

Authors

Heloine Martins Leite Universidade Federal de Juiz de Fora https://orcid.org/0000-0002-0488-2923
Marcos Daniel Silva Pinheiro Universidade Federal de Juiz de Fora https://orcid.org/0000-0003-2278-4822
Daisy Cristina Monteiro dos Santos Universidade Federal de Juiz de Fora https://orcid.org/0000-0002-8304-4986
Karolina Dias Campos Universidade Federal de Juiz de Fora https://orcid.org/0009-0003-2131-4754
Lorena Bruna Pereira de Oliveira Universidade Vale do Rio Doce https://orcid.org/0000-0001-7783-2700
Lucia Alves de Oliveira Fraga Universidade Federal de Juiz de Fora

DOI:

https://doi.org/10.47878/hi.2023.v48.39317

Keywords:

Leprosy, Diagnosis, Serology

Abstract

Leprosy is a chronic and infectious disease caused by Mycobacterium leprae (M. leprae). It has high infectivity and low pathogenicity. The aim of this study was to report the identification of a patient with multibacillary leprosy using the serological test (LID) during an active search. A 54-year-old male patient, living in Governador Valadares, Minas Gerais, Brazil, from the active search of the Leprosy
Research Center (NuPqHans/UFJF-GV), presented a positive serological test for recombinant bacillus proteins (ML0405/ML2331). He was referred to the Reference Center for Endemic Diseases and Special Programs (CREDENPES), complaining of skin lesions and nodules all over his body, and reported a history of head trauma, occasional dizziness, numbness in his feet, and nosebleeds. The patient presented positive bacilloscopy and biopsy results, concluding the diagnosis of multibacillary leprosy and receiving the indicated multidrug therapy. After three months of treatment, there was a reduction in the area/diameter of the lesions on the abdomen, indicating the effectiveness of the treatment. The positive result of the serological test (LID) allowed the identification of a multibacillary patient, who until then had not been diagnosed with leprosy. In addition, the use of the LID serological test in active search activities in endemic areas for early diagnosis can contribute to the zero-leprosy concept stipulated by the World Health Organization.

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