Keywords
toxoplasmosis
mice
white
chranically infected with Toxoplasma gondii
response to pentetrazol
mice
white
chranically infected with Toxoplasma gondii
response to pentetrazol
How to Cite
1.
Chieffi PP, Nascimento E do. Response to pentetrazol in albino mice with chronic toxoplasma gondii infection. Rev Inst Adolfo Lutz [Internet]. 1982 Dec. 30 [cited 2024 Jul. 22];42(1-2):59-62. Available from: https://periodicos.saude.sp.gov.br/RIAL/article/view/36780
Abstract
The response to various doses of pentetrazol was studied in white mice chranically infected with a low-virulence strain of Toxoplasma gondii. Uninfected mice of the same source were also tested. Therate of occurrence of mioclonic reactions, freezing, and convulsion after sub-lethal doses of pentetrazol was studied through administration of 32, 36, 38, 41 and 44 mg per kg of animal weight, respectively, to each of twenty mice. Low rates of response under ali tested parameters was observed; this presumably resulting from an alteration in the regulatory mechanism of the central nervous system.
References
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12. STRECHT, R.G.A.; STRECHT, S.J.E.; LEYTHAM, G.W.H. & KERSHAW, W.E. - The effect of schistosomiasis upon discrimination learning and activity in mice. I. An acute infection. Ann. trop. Med. Parasitol., 54:376-80, 1960.
13. STRECHT, S.J.E.; STRECHT, R.G.A.; LEYTHAM, G.W.H. & KERSHA W, W.E. - Discrimination learning and schistosomiasis in the rat: a low-g rade infection of several months' duration. Ann. trapo Med. Parasitol., 54 :483-6, 1960.
2. CASTILHO, E.A. - An estimation of the incidence of congenítal toxoplasmosis in São Paulo city, Brazil. Rev, Inst. Med. trop. S. Paulo, 18:202-5, 1976.
3. HOARE, C.A. - The developmental stages of Toxoplasma. J. trod. Med. Hug., 75: 56-8, 1972.
4. HUTCHISON, W.M.; ATTKEN, P.P. & WELLS, B.W.P. - Chronic Toxoplasma infections and familiarity-novelty discrimination in the mouse. Ann. trop. Med. Parasitol., 74:145-50, 1980.
5. HUTCHISON, W.M.; AITKEN, P.P. & WELLS, B.W.P. - Chronic Toxoplasma infections and motor performance in the mouse. Ann. trop. Med. Parasitol., 74: 507-10, 198{).
6. HUTCHISON, W.M.; BRADLEY, M.; CHEYNE, W.M.; WELLS, B.W.P. & HAY, J. - Behavioural abnormalities in Toxoplasma-infectedmice. Ann. trop. Med. Parasitol., 74:337-45, 1980.
7. JAMRA, L.M.F. & GUIMARÃES, E.C. Conversão sorológica para toxoplasmose em crianças de um centro de saúde de São Paulo. Rev. Inst. Med. trop. S. Paulo, 23: 133-7, 1981.
8. KERSHAW, W.E.; LEYTHAM, G.W.H. & DICKERSON, G. - The effect of schistosomiasis on animal intelligence. Ann. trop. Med. Parasitol, 53: 504-8, 1959.
9. MC COLM, A.A.; HUTCHISON, W.M. -& SUM, J.C. - The prevalence of Toxoplasma gondii in meat animaIs and cats in Central Scotland. Ann. trop. Med. Parasitol., 75: 157 -64, 1981.
10. SIIM, J.C.; BIERING-SORENSON, U. & MOLLER, T. - Toxoplasmosis in domestic animaIs. Adv. Veto Sci., 8:335-429, 1963.
11. STRECH, R.G.A.; LEYTHAM, G.W.H. & KERSHA W, W.E. - The effect of acute schistosomiasis upon learning in rats under different levels of motivation. Ann. trapo Med. Parasitol., 54:487-92, 1960.
12. STRECHT, R.G.A.; STRECHT, S.J.E.; LEYTHAM, G.W.H. & KERSHAW, W.E. - The effect of schistosomiasis upon discrimination learning and activity in mice. I. An acute infection. Ann. trop. Med. Parasitol., 54:376-80, 1960.
13. STRECHT, S.J.E.; STRECHT, R.G.A.; LEYTHAM, G.W.H. & KERSHA W, W.E. - Discrimination learning and schistosomiasis in the rat: a low-g rade infection of several months' duration. Ann. trapo Med. Parasitol., 54 :483-6, 1960.
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Copyright (c) 1982 Instituto Adolfo Lutz Journal
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