Type 2 reaction (multiforme erythema-like) as the first clinicai manifestation of leprosy in the lepromatous range

Authors

  • Jaison Antônio Barreto Barreto Médico Dermatologista do Instituto Lauro de Souza Lima. Hansenologista. Mestre em Ciências.
  • lana Costa Freitas Médica Residente do 1° Ano do Programa de Residência Médica em Dermatologia do Instituto Lauro de Souza Lima.

DOI:

https://doi.org/10.47878/hi.2005.v30.35493

Keywords:

leprosy, type 2 reaction, antibiotics

Abstract

A 51 years old man presented inguinal lymphadenitis followed by fever. He was treated with antibiotics and developed multiforme erythema like lesions. A skin biopsy showed active leprosy in the lepromatous range plus type 2 reaction. There wasn't epidemiological data or cutaneous lesions suggestive of leprosy, and no signs or symptoms of neural damage was found. The case showed two peculiarities: type 2 reaction as the first manifestation of leprosy (before beginning of multidrugtherapy) and presenting as multiforme erythema-like lesions. The authors discuss the pathogenesis of these manifestations, and remember that is important to think in leprosy face to multiforme erythema-like lesions in endemic areas.

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References

1 Fleury RN. Patologia e manifestações viscerais. In: Opromolla, DVA. Edditor, Noções de hansenologia. Baum; Centro de Estudos Dr. Reynaldo Quagliato; 2000, p. 63-71,
2 Harter PP. L'Erythema nodosum leprosum de Murata. Revue de la littérature. Étude de 185 cas. Buli Soe Path Ex 1965;58(3):335- 400.
3 Nogueira MES, Vilani-Moreno FR, Silva EA, Arruda MSP. Imunologia, In: Opromolla, DVA. Edditor. Noções de hansenologia. Bauru: Centro de Estudos Dr. Reynaldo Quagliato; 2000. p. 27-42
4 Harboe M. The immunology of leprosy. In: Hastings RC. Editor. Leprosy. Edinburgh; Churchill Livingstone; 1985. p 77-78,
5 Hastings RC. Clinicai aspeets - reactional episodes. Int ( Leprosy 1979;47:348.
5 job CK. Pathology of leprosy. In: Hastings RC. Editor. Leprosy Edinburgh;Churchill Livingstone; 1994. p. 193-224.
7 Ridley DS. La biopsia de la piei en la lepra. 2ed. Suiça:Ciba Geigy SA; 1987.
8 Moraes MO, Sarno EN, Almeida AS, Saraiva BC, Nery JA, Martins RC, Sampaio EP. Cytokine mRNA expression in leprosy: a possible role for interferon-gamma and interleukin-12 in reactions (RR and END. Scand J Immunol 1999; 50(5):541-9.
9 Souza Lima LS, Maurano F. Reação leprótica. Ministério da Educação e Saúde. Departamento Nacional de Saúde. Serviço Nacional Lepra. Rio de Janeiro, 1949.

Published

2005-06-30

How to Cite

1.
Barreto JAB, Freitas lana C. Type 2 reaction (multiforme erythema-like) as the first clinicai manifestation of leprosy in the lepromatous range. Hansen. Int. [Internet]. 2005 Jun. 30 [cited 2024 Jul. 22];30(1):25-7. Available from: https://periodicos.saude.sp.gov.br/hansenologia/article/view/35493