Risco microbiológico associado a drogas vegetais psicoativas adquiridas no comércio popular

Julino Assunção Rodrigues Soares Neto; Eliana Rodrigues; Adriana Aparecida Buzzo Almódovar; Tatiana Caldas Pereira; Adriana Bugno

doi:10.53393/rial.2012.v71.32445

Vol. 71 No. 2 (2012), BRIEF COMMUNICATION

Vol. 71 No. 2 (2012)

Microbiological contamination risk of psychoactive herbal drugs purchased in informal trade

BRIEF COMMUNICATION

https://doi.org/10.53393/rial.2012.v71.32445

Published 2012-02-01

Julino Assunção Rodrigues Soares Neto⁺⁻
Eliana Rodrigues⁺⁻
Adriana Aparecida Buzzo Almódovar⁺⁻
Tatiana Caldas Pereira⁺⁻
Adriana Bugno⁺⁻

Julino Assunção Rodrigues Soares Neto

Universidade Federal de São Paulo, Departamento de Ciências Biológicas, Diadema, SP

Eliana Rodrigues

Universidade Federal de São Paulo, Departamento de Ciências Biológicas, Diadema, SP

Adriana Aparecida Buzzo Almódovar

Instituto Adolfo Lutz, Centro de Medicamentos, Cosméticos e Saneantes, São Paulo, SP

https://orcid.org/0000-0001-5572-9091

Tatiana Caldas Pereira

Instituto Adolfo Lutz, Núcleo de Ensaios Biológicos e de Segurança, São Paulo, SP

Adriana Bugno

Instituto Adolfo Lutz, Centro de Medicamentos, Cosméticos e Saneantes, Núcleo de Ensaios Biológicos e de Segurança, São Paulo, SP

PDF (Português (Brasil))

Keywords

medicinal plants
contamination
mycotoxins
informal trade
health risk

How to Cite

1.

Soares Neto JAR, Rodrigues E, Almódovar AAB, Pereira TC, Bugno A. Microbiological contamination risk of psychoactive herbal drugs purchased in informal trade. Rev Inst Adolfo Lutz [Internet]. 2012 Feb. 1 [cited 2024 May 20];71(2):420-3. Available from: https://periodicos.saude.sp.gov.br/RIAL/article/view/32445

Abstract

This study evaluated the microbiological contamination risk of 70 samples of 18 psychoactive herbal drugs purchased in the informal trade in Diadema, SP. This analysis was performed according to the parameters established by the World Health Organization (WHO) and Brazilian Pharmacopeia. The microbiological quality concerning the bioburden and the occurrence of food-borne risk indicators were evaluated following the official compendia. Besides, the potential production of aflatoxins, ochratoxin A and citrinin by the isolated fungi was assessed. Of the analyzed herbal drugs, 66.7% samples did not comply with the WHO standards in relation to bacterial and fungal load. In accordance with the microorganism contamination risk indicators defined by the Brazilian Pharmacopoeia, the rate of noncompliant herbal drugs increased to 94.4% due to the detection of Enterobacter spp and Aspergillus flavus. In relation to toxigenic potential, none of the fungal isolates showed capability of producing ochratoxin A or citrinin, and four (3.9%) Aspergillus flavus isolates only were able to produce aflatoxins B1 and B2. The poor microbiological quality indicated the need to adequate the herbal drugs informal trade in order to preserve the consumer’s health.

https://doi.org/10.53393/rial.2012.v71.32445

PDF (Português (Brasil))

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